The ability of drugs to epigenetically affect gene expression is considered one of the likely mechanisms of unwanted side reactions. Whole-genome DNA methylation (MspI/HpaII) and its fragmentation in blood lymphocytes of rats against the background.

A detailed review of literature sources, in which studies of the microbiome of the endometrium in women of reproductive age are presented. The role of the uterine microbiome in the development of endometrial hyperplasia and other proliferative diseases.

Optimal optical correction on the accommodative apparatus of the myopic eye. The nearest point of clear vision in patients with mild myopia. Study the accommodative function of the eyes. Refractive therapy with orthokeratology lenses all patients.

Purulent-inflammatory complications of soft tissues in patients with diabetes mellitus as a complex surgical problem. A study of the influence of ozone therapy on the course of purulent-inflammatory processes in diabetes, improvement regulation of blood.

In the study effect ofportal hypertension on the condition of the hemomicrocirculatory tract of the skin male white nonlinear rats was studied. Hypertension was simulated by applying a ligature to the portal vein according to the conventional method.

A description of the impact of anxiety, depression and stress on the occurrence, exacerbation and course of cardiovascular diseases. A connection between anxiety and depression. Determining the impact of everyday stress on the psycho-emotional state.

Optimizing lipid-lowering therapy and achieving it in three ways: increasing the dosage of statins. The pathogenesis of immune inflammatory reactions and endothelial dysfunction ischemic heart disease in combination with systemic inflammatory diseases.

Atrial fibrillation is one of the most common persistent cardiac arrhythmias and is associated with an increased risk of mortality. Features of the effect of thyroid-stimulating hormone on relapse after radiofrequency ablation in atrial fibrillation.

The study influence of the cardio-nephroprotective therapy on serum markers of cardiovascular risk in patients with chronic kidney disease. The possibility of practical use of FGF-23 and Klotho as an early diagnostic marker of cardiovascular risk.

Hepatitis B is one of the major problems in medical science and practical public health. The dynamics of changes in the parameters of prooxidant-antioxidant homeostasis in patients with acute hepatitis B with chronic use alcohol in doses hepatotoxic.

A key factor in the development of neoangiogenesis in diabetic retinopath in patients with type 2 diabetes mellitus (DM2) is Vascular Endothelial Growth Factor (VEGF). The important role of VEGFA gene polymorphisms is highlighted by numerous studies.

The basis for effects of electromagnetic radiation on microorganisms. Specific effects on microorganisms by the Apparatus "KSK-BARS". The treatment of participants in space missions as an to antibacterial and antiviral therapy by non-pharmaceutic means.

The goal is to evaluate the informativeness of additional laboratory indicators in the diagnosis of viral hepatitis B and C in pregnant women. Serological studies, polymerase chain reaction, biochemical and immunological blood tests were carried out.

Composition of the rating of the most dangerous and safest sports of the Summer Olympics in Beijing. Athletes who competed in boxing received the most injuries, canoeing was less traumatic. In total, 1,055 athletes were injured in the Olympic arenas.

Features and classification of injuries of the maxillofacial region. Sprains and fractures of teeth. Fractures of the mandible. Jawfall: causes, clinical manifestations. The anatomical shape of damaged residues. Treatment of mandibular fractures.

Study of the dynamics of nephrectomy, kidney injury as its causes. Determination, substantiation of the nature of changes in absolute indicators over a long period, their intensity by years of study. Regional characteristics of the frequency of injuries.

Огляд insilico-досліджень з молекулярних механізмів фармакологічної дії кверцетину як потенційного мультитаргетного препарату. Сучасні дані щодо найпоширеніших insilico-досліджень кверцетину – його міжмолекулярних комплексів з різними білками-мішенями.

According to the results of the behavioral study, the values of the hygienic in dex, the gingivitis index and the periapical index before the start of the course of basic therapy for endo-peri odontal complications were comparable in both study groups.

Comprehensive examination of children with obesity and arterial hypertension, clinical and metabolic assessment of their condition. A high, accelerated rate of sexual development, a decrease in the quality of life and a high frequency of pathology.

Intentional replantation is an accepted endodontic treatment procedure in which a tooth is extracted and treated outside the oral cavity and then inserted into its socket. Intentional replantation is indicated when other endodontic treatments have failed.

Study the interaction of adaptor protein Ruk/CIN85 SH3 domains with endogenous indicator Tks4 in tumor cells of different tissue origins. Research of physiological responses of cell immunity in mice. New multiple molecular forms of adaptor protein.

Pharmacological activity of the main derivatives of 1,5-benzodiazepines. Interaction of 4-phenyl- and 4-methyl-2,3-dihydro-1H-1,5-benzodiazepinones-2 with epichlorohydrin under various conditions. The use of hard and soft basic reaction systems.

An urgent problem is considered - providing first aid to victims of various burns in the conditions of hostilities during a full-scale invasion by the troops of the aggressor country. The medical aspect of the concept of burns and their types is revealed.

The post endodontic is a relatively rare occurrence, but the sudden increase in patient symptoms necessitates a focused and active treatment plan. Discusses these facets of the flare-up: prevention and how to manage the patient once the flare-up occurs.

Causes of interappointment pain. Presence of pathogenic bacteria. Presence of virulent clonal types. Microbial synergism or additism. Number of microbial cells. Apical extrusion of debris. Secondary intraradicular infections. Non-microbial causes.

The prevalence of noncommunicable diseases. Risk factors around the world that require a comprehensive response from the health system. Measures to combat the epidemic of noncommunicable diseases. National program of screening preventive examinations.

The association between diabetes and increased severity of COVID-19 outcomes. Disruptions in T-cell function, cytokine storms, and endothelial dysfunction of insights into the mechanistic underpinnings of the heightened risk in diabetic individuals.

Look Professor the need in experimental and clinical studies to confirm the effectiveness of transplantation of hematopoietic stem cells is umbilical cord blood. Analysis of the effectiveness of treatment of hematologic and non-hematologic diseases.

Rating by Susana Gomez umbilical cord blood among other sources of hematopoietic stem cells, the experience of its clinical application and comparative characteristics of bone marrow and peripheral blood. Attitude Susani to private cord blood banks.

Аnalysis of Doppler echocardiographic indexes in patients (with syndrome and without UCTD) with first diagnosed Q-myocardial. The features of intracardial hemodynamic disorders in patients with Q-MI. based on undifferentiated connective tissue dysplasia.