The relevance of studying the triggering mechanisms of cervical carcinogenesis is due to the high frequency of human papillomavirus infection among young women. The effect of folate on DNA methylation and expression of the tumor suppressor FHIT protein.

Immunosuppressive therapy regiments. Analysis of the clinical use of mTOR inhibitors has provided evidence of comparative frequency rate of wound complications and terms of surgical wound healing in the treatment with everolimus and routine therapy.

The results of clinical use of mTOR inhibitors, in particular, everolimus, in immunosuppressive therapy regimens. Reasons why immunosuppressive therapy regimens including mTOR inhibitors are preferred in patients with high and moderate risk of graft loss.

The use of a drinking diet with a reduced content of deuterium - a method of reducing liver tissue damage in the simulation of hypoxia by clamping the hepatoduodenal ligament. The liver - an organ that supports biochemical homeokinesis in the body.

46 different volatile compounds were identified. The inappropriate storage conditions of olives had a negative impact on the aroma profiles of oils. The most abundant compounds were hexanal, a-farnesene, dimethylpalmitamine, and a-Farnesene, 2-hexanal.

Administration of 8-(benzenesulfonylamino)-quinoline was accompanied by the development of epileptiform seizures and an intravital reaction in the hippocampus. The intensity of the reaction was correlated with the duration of seizures in animals.

We examined 82 patients with stage II hypertension. 50 of them had frequent ventricular arrhythmias according to Holter monitoring. 32 patients had verified hypertension without any heart rhythm disorders, another 30 healthy individuals were included.

Diurnal organization of glutathione peroxidase activity in healthy volunteers. Violation of regimen of illumination with prolongation of activity at night time in healthy volunteers, desorganization of biological rhythms of antioxidant defence values.

Schizophrenia is an urgent problem in modern medicine. A study of the concentration of cytokines with pro-inflammatory and anti-inflammatory activity in individuals with different types of paranoid schizophrenia (continuously progressive and episodic).

Expression level of immunohistochemical markers such as HepPar-1, AFP, CK7, CK20. The area of immunopositive cells in cholangiocellular liver cancer, and their differences from hepatocellular carcinoma. Histopathological, histochemical research of treph.

Organ-specific biliation and biligenic functions of the liver. The dynamics of indicators of biligenic function of the liver in response to cranial skeletal trauma associated with haemorrhage. Analysis of the factors accelerating liver dysfunction.

Study of the state of the indicators of the cellular link of immunity in the body of experimental animals with simulated AGP on the background of obesity. Comparison with groups of animals with obesity and animals with acute disseminated peritonitis.

Determination of dependence of the condition of central retina in patients with proliferative diabetic retinopathy on the duration of type 2 diabetes mellitus and the glycemic level. The influence of DM2 on the progression of DR and on visual functions.

The new peptide-specific antibodies against the isoform 2 of translation elongation factor 1A (eEF1A2) and determine its presence in the postoperative samples of human breast, lung and stomach tumor tissues. The normal tissues surrounding tumors.

Исследование врожденных пороков развития, обусловленных мутациями гена СHD7, характерных для CHARGE-синдрома. Рассмотрение клинических проявлений, особенностей диагностики и лечения CHARGE-синдрома. Роль гена CHD7 в развитии клеток нервного гребня.

Main characteristics of chelator preparations and the critical examination of the extensive literature on the their effectiveness. Clinical results on the application and the order in which the chelator should be used. The results of the dental surgery.

Prospects for study of sulfones. Develop of the preparative method of alkylation of 4-methyl-2-oxo-1,2-dihydroquinoline-6-sulfinic acid with allyl bromide. Characteristic of synthesis scheme of 6-allylsulfonyl-4-methyl-1,2-dihydroquinoline-2-one.

Pathogenetic mechanisms of psychopathologic disturbances formation. Early diagnosis of psychopathological conditions and disorders of the autistic spectrum. Development and testing of methods of interactive models of medical and psychological assistance.

The problem of disposal of the pharmaceutical industry, the assessment of its relevance at the present stage, perspectives permission. Harmful substances emitted during the production of pesticides, chlorine compounds. Legal and technical support.

Alcohol abuse and dependence. Alcoholism: main stereotypes, definitions, and criteria. Main types of disease. Physiological effects of chronic alcohol abuse. The famous twelve steps of alcoholics anonymos. Approaches to treatment for alcoholism.

To study the role of bacterial and viral pathogens in the occurrence of exacerbations of chronic obstructive pulmonary disease. The main methods of identification of pathogens, determination of their sensitivity to various groups of antibacterial drugs.

Research on the development of inflammatory and dystrophic processes of mucous membranes of the human stomach. Study of the pathogenetic mechanism of a combination of duodenal ulcers and chronic periodontitis. Treatment of chronic atrophic gastritis.

A narrative literature overview of Fabry disease, with a clinical case presentation. Clinical, neurological, laboratory, and instrumental analysis of Fabry disease in a young white adult admitted to Regional clinical center of neurosurgery and neurology.

Pathogenesis and clinical manifestations of rickets. Description of calcium-deficient rickets with secondarily elevated parathyroid hormone levels and phosphate-deficient rickets. Place of vitamin D deficiency in the mechanisms of its development.

The relationship between pulp and periapical diseases. The stages of disease progression in tissue as a result of a stimulus or irritant that is not removed or treated. Periapical inflammation without pulp infection. Classifications of periapical diseases

The concept and clinical picture of gastritis, the prerequisites for its development, symptoms. The diagnosis of this disease and the development of a scheme for its treatment, a prognosis for the recovery of the patient. Etiology and pathogenesis.

Study of a clinical case of autoimmune encephalitis of the brainstem in combination with a congenital malformation of the brain in a child. Identification of concomitant congenital pathology of the cerebral cortex as a cause of childhood hemiparesis.

The effectiveness of various methods of treatment of patients with gonarthrosis at the outpatient stage and reveal the difference in clinical results. Retrospective analysis of 89 patients who received different types of conservative treatment.

Study of the incidence of liver pathologies and the nature of its manifestations in Covid-19 patients with a fatal outcome. Impact of SARS-CoV-2 virus liver cells and cells lining the intra- and extrahepatic bile ducts. Inflammation of blood clots.

Research parasitic disease caused by the larvae of Ascaris migration to various organs. Analysis of the duration of the disease and relapse of multiple organ allergiс nature. Epidemiological studies of toxocariasis in children of different age groups.